Clinical dose of Bioferrin, Turmeric and L-Alynyl Glutamine in an herbalomic support blend. Studies reveal that short chain fatty acids (SCFA), flavonoids, growth factors, phytotherapeutics such as berberine are powerful influences for healthy G.I. tract integrity. Supporting an already healthy epithelial barrier is of paramount importance and foundational to health.

#467 LGUT (Leaky Gut Mastery)
Gastrointestinal permeability (leaky gut) severely impacts the normal, healthy human immune functions. Some 70% of the human
immune system is centered in the intestines. Research reveals that key botanical nutrients help the normal regulatory processes and
help restore tissue integrity to the intestinal epithelium and microbiome processes. Some nutrients provide protective molecules by
up-regulating the tight junction protein claudin and down-regulating the protein zonulin. Other studies reveal that short chain fatty acids
(SCFA), flavonoids, growth factors, phytotherapeutics such as berberine are powerful influences for healthy G.I. tract integrity. Preserving
the integrity of the epithelial barrier and supporting the normal maintenance processes are of paramount importance and foundational to
health and healing programs.

 INDICATIONS
• Leaky gut normal repair processes
• Intestinal tissue nutrition
• Support the normal “set point” of immunological
activities
• Tight junction integrity
• Support normal repair processes needed by some people
who are damaged by hybridized grain ingestion

KEY COMPONENTS
• Lion’s Mane Mushroom – Provides beta glucan
polysaccharides, fatty acids, and polypeptides in
support of normal intestinal endothelial maintenance
activity. Oleanolic acids and adenosine support immune
modulatory processes such as the induction of interferons
necessary for intestinal integrity. Supports normal
mucous barrier function.
• Gogi Berry – A nutrient dense food featuring
phytonutrients and antioxidants that help support healthy
intestinal functions.
• L-Alanyl-L-Glutamine – Supports the normal exchange
of nitrogen between tissues and aids normal glucose
metabolism and cellular hydration. Supports the glucosealanine cycle. Glutamine is the primary transporter
between cells of nitrogen derived from protein
breakdown, and it stimulates glucose-like peptide-1
(GLP-1). Supports normal glycogen synthesis.
• RNA/DNA Duodenum Tissue Factors – Supports the
integrity of the duodenal intestines.
• Acetic Acid – Assists normal digestion and mobilization of
sugars needed for energy and maintenance.
• Goldenseal (Hydrastis canadensis) – The plant alkaloid,
berberine, is one of many alkaloids found in Goldenseal
Root. Recent research shows berberine can help protect
against TNF - a mediated barrier defect in a human colon
cell model. Berberine is also a powerful supporter of
immune relations with many bacterial and fungal species.
• Genistein – Strong antioxidant, removes damaging
free radicals and reduces lipid peroxidation. Genistein
increases the activity of other antioxidant enzymes such
as glutathione peroxidase, superoxide dismutase and
glutathione reductase. Studies show that genistein also
influences the growth of cells which are not hormonedependent and helps maintain proper cellular function.
• Rhubarb – Alkalizing food, contains lutein, vitamin k, and
antioxidants (incl. lycopene). A bowel tonic and supporter
of normal purification processes. Provides vitamins, K, C,
A, and B complexes. Helps regulate intestinal health.
• Black Radish – A food frequently cited as supportive for the entire
gastrointestinal tract and liver. Contains antioxidant properties that
eliminate the free radicals that are often responsible for causing
oxidative damage to cell membranes. Helps support normal
purification processes.
• Turmeric – Extremely well researched and is a valuable herb that
helps the secretory processes of digestive fluids. Antioxidant.
• Bioferrin – A unique, low-iron form of lactoferrin, a protein clinically
proven to benefit the G.I. tract’s normal, healthy activities. Supports
the immune system in its normal viral vigilance.
• Aloe Vera Leaf – Provides healing mucopolysaccharides for
intestinal repair and integrity.
• Fructooligosaccharides/Inulin – Prebiotics that promotes
proliferation of probiotic species that help maintain normal
gastrointestinal flora.

CONTRAINDICATIONS
None when used as directed.

CLINICIAN CONSENSUS
• Repair Intestinal Endothelium Integrity:
#467 LGUT - Leaky Gut Mastery
#6 Restore
#200 AO - Aloe Vera

BACKGROUND
Dr. Shayne Morris and Systemic Formulas have applied the latest
herbalomic™ research on Leaky Gut and Intestinal Hyperpermeability
to create this gut permeability, tissue integrity support formula. LGUT
provides specific botanical and nutritional ingredients to support the
body’s inherent gastrointestinal maintenance processes.

 SYNERGISTIC CONSIDERATIONS
• #697 ZGlutn - Gluten Control
• #6 Restore
• #2 Builder
• #200 AO - Aloe Vera
• #404 BIND - Toxin Elimination
• #433 GCEL - Intracellular Glutathione
• #131 FBR - Fibers for Intestinal Health
• #14 C - Colon
• #100/#138 ABC - Acidophilus & Bifidus Complex & MBC -
Microbiome Colonizer
• #17 D - Digest